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Abstract #3011

Fitting DCE-MRI Data in the Liver with a Dual-Inlet Model: Choice of Venous & Arterial Delay Parameters

Steven Sourbron1, Wieland Sommer2, Christoph J. Zech2, Maximilian F. Reiser2, Karin A. Herrmann2

1Division of Medical Physics, University of Leeds, Leeds, United Kingdom; 2Department of Clinical Radiology, University of Munich, Munich, Germany

The choice of arterial and venous delay times in DCE-MRI of the liver has a strong effect on the measured parameters. In this study a number of alternative methods are applied to patient data and compared. Results show that an arterial delay time is necessary to obtain a good fit to the data, but including an additional venous delay causes unstable and overestimated perfusion values. It is concluded that DCE-MRI data in the liver are best analysed by fitting an arterial delay, and assuming that the venous delay is zero.