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Abstract #3036

Comparative Study of SSFP Lung MRI at 1.5T with High Resolution Computed Tomography in Patients with Interstitial Lung Fibrosis

Smitha Rajaram1, Andy James Swift1,2, David Capener1, Robin Condliffe3, Charlie Elliot3, Judith Hurdman3, Christine Davies4, Catherine Hill4, David G. Kiely3, Jim M. Wild1

1Academic Unit of Radiology, University of Sheffield, Sheffield, Yorkshire, United Kingdom; 2NIHR Cardiovascular Biomedical Research Unit, Sheffield, United Kingdom; 3Pulmonary Vascular Disease Unit, Royal Hallamshire Hospital, Sheffield; 4Department of Radiology, Royal Hallamshire Hospital, Sheffield

Interstitial lung disease is characterised by inflammation and scarring of the pulmonary interstitium leading to increased signal from the diseased lung tissue. The purpose of our study was to compare 1.5 SSFP MRI of the lung parenchyma with high resolution computed tomography (HRCT), which is considered as the gold standard imaging modality in assessment of patients with interstitial lung disease. MR lung imaging has good specificity and sensitivity for diagnosing pulmonary fibrosis. However our results show that lung MRI has a poor sensitivity (78.5%) for identifying mild degree of pulmonary fibrosis but high sensitivity for severe disease.