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Abstract #3219

Experimental Investigation into the Relationship between T2* & T2 in Cartilages at 3T

Yongxian Qian1, Ashley A. Williams2, Constance R. Chu2, Fernando E. Boada1

1Radiology, University of Pittsburgh, Pittsburgh, PA, United States; 2Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA, United States

When voxel size is decreased (or image resolution is increased), the impact of encoding gradient and B0-field inhomogeneity on T2* time is decreased and as a result, T2* time is supposed to be closer to T2 value. This work, however, shows that T2* in cartilage explants from human knees does not approach to T2 value when increasing image resolution. The reason for this might be that inhomogeneous microenvironment in tissue dominates local field and T2* values.