Riccardo Lattanzi1,2, Anna Krigel3,
Catherine Petchprapa2, Artem V. Mikheev2, Kevin Dunham2,
Soterios Gyftopoulos2, Tallas Charles Mamisch4, Young
Jo Kim5, Henry Rusinek2, Michael Recht2,
Christian Glaser1,2
1Center for Biomedical
Imaging, New York University Langone Medical Center, New York, NY, United
States; 2Radiology, New York University Langone Medical Center,
New York, NY, United States; 3New York University School of
Medicine, New York, NY, United States; 4Clinical Research,
University of Bern, Bern, Switzerland; 5Orthopedic Surgery,
Children's Hospital, Boston, MA, United States
Corrective surgical procedures can delay osteoarthritis for patients with femoroacetabular impingement (FAI) if hip articular cartilage degeneration is diagnosed in its early stages. Delayed Gadolinium-Enhanced MRI of Cartilage (dGEMRIC) is used for the detection of early biochemical changes in articular cartilage. A single threshold value for all cases may not be indicated to discriminate between normal and abnormal cartilage in dGEMRIC T1 maps. A method is proposed to standardize dGEMRIC measurements in order to remove the effect of inter- and intra-patient variability. Comparison with arthroscopic findings showed 66% accuracy in assessing anterior-superior, superior and posterior-superior cartilage in 10 FAI patients.
Keywords