Scott Puckhaber1, Matthew Fenty2,
1Duke University School of
Medicine, Durham, NC, United States; 2CMROI, Radiology, University
of Pennsylvania, Philadelphia, PA, United States; 3Musculoskeletal
Imaging, Department of Radiology, Hospital of the University of Pennsylvania,
Philadelphia, PA, United States
Glenohumeral arthritis is a disabling condition and may severely affect quality of life and activities of recreation and daily living. With shoulder injuries, either traumatic or from repeated stresses, the integrity of the cartilage may become compromised due to several factors such as abnormal loading conditions and repeated stresses. Osteoarthritic changes to articular cartilage such as loss and breakdown of proteoglycan molecules has been quantified with high sensitivity with T1ρ MRI . The aim of this study was to develop a T1ρ MRI protocol to accurately quantify biochemical properties of the glenohumeral articular cartilage to monitor the development of cartilage degeneration in vivo.