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Abstract #3240

Estimating the Short-Time Elastic Modulus of Cartilage using T1ρ & T2

Kathryn E. Keenan1,2, Thor Besier1, R. Lane Smith1,2, Gary S. Beaupre1,2, Garry E. Gold1

1Stanford University, Stanford, CA, United States; 2Bone & Joint RR&D Center, VAHCS, Palo Alto, CA, United States

Cartilage material properties have been related to MR parameters, but initial elastic modulus, which is useful in subject-specific finite element models of walking, has not been studied. Initial elastic modulus (E0) of human patellar cartilage was regressed with T1ρ and T2 relaxation times. T1ρ did not individually correlate with E0, nor did T2. However, sGAG and collagen were individually correlated with E0. T1ρ was related to sGAG, while T2 was not related to collagen. T1ρ and T2 were significantly correlated in this study.