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Abstract #3263

Reduced T2* Values in Soleus Muscle of Type 2 Diabetes Mellitus

Chun S. Zuo1, Donald Simonson2, Young-Hoon Sung1, Rosemond Villafuerte1, Perry F. Renshaw1

1McLean Hospital, Boston, MA, United States; 2Brigham & Womens Hospital, Boston, MA, United States

We have examined T2* of soleus in Type 2 Diabetes Mellitus (T2DM) compared to that of normal healthy subjects in a cross-sectional study. We found that soleus T2* is significantly correlated with age and the presence of diabetes. Among factors that may contribute to T2* values, the lowered T2* value in the T2DM soleus muscle is most consistent with poor regional microvascular circulation which suggests that the T2DM soleus is likely under tissue oxygenation stress.