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Abstract #3338

Accuracy of Non-Contrast Fresh-Blood MRA for the Assessment of Lower Extremity Peripheral Vascular Disease

Timothy S. E. Albert, M.D.1, Erin J. Kelly, Ph.D.2, Patrik Zetterlund, M.D.1, Connie Luna, R.T.1, Nancy Yellin, RN1, Mitsue Miyazaki, Ph.D.3

1Salinas Valley Memorial Hospital Cardiovascular Diagnostic Center, Monterey, CA, United States; 2Toshiba America Medical Systems, Tustin, CA; 3Toshiba Medical Research Institute USA, Inc, Vernon Hills, IL

A clinical population with a variety of vascular disease underwent a non-contrast 3D FS-FBI MRI exam and an X-Ray angiography exam. The accuracy of FS-FBI was evaluated in the assessment of various vascular diseases compared to conventional X-Ray Angiography. Using a 25-segment model blinded analysis of FBI images and DSA images, both image quality (poor-1; good-2; excellent-3) and stenotic severity (Non Diagnostic (ND), 0-25%, 26-50%, 51-75%, 76-99%, total occlusion) were compared. Overall clinical accuracy revealed a sensitivity of 0.90, specificity 0.94, positive predictive value 0.81, and negative predictive value of 0.97. In comparison to DSA, FBI shows high clinical accuracy.