Christakis Constantinides1, Daniel Rueckert2,
Dimitrios Perperidis1
1Mechanical &
Manufacturing Engineering,
This work quantifies and compares regional and global cardiac performance in humans and mice. Such effort attempts to provide evidence to validate the hypothesis of functional scaling from mouse to human. Its potential clinical significance is in mouse phenotyping for determining myocardial dysfunction, in correlation with perfusion and metabolism.
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