High Resolution CMRO2 in Visual Cortex of Macaca Mulatta

Yvette Bohraus¹, Nikos K. Logothetis^1,2, Jozien Goense¹

Current fMRI-methods are based on changes in cerebral blood flow and/or oxygenation. Since these methods measure hemodynamic signals, changes in BOLD or CBF may not always accurately reflect changes in the actual energy use of the brain. We determined CMRO₂ in macaques during visual stimulation at high resolution. The CMRO₂ values and the ratio of fractional CBF and CMRO₂ changes were consistent with those reported in the literature.