Matthew Man Hin Cheung1,2, Iris Y. Zhou1,2,
Kevin C. Chan1,2, Frank Y. Lee1,2, Leon C. Ho1,2,
Condon Lau1,2, Ed X. Wu1,2
1Laboratory of Biomedical
Imaging & Signal Processing, the University of Hong Kong, Pokfulam, Hong
Kong SAR, China, People's Republic of; 2Department of Electrical
& Electronic Engineering, the University of Hong Kong, Pokfulam, Hong
Kong SAR, China, People's Republic of
In this study, auditory system was investigated in rodents by BOLD fMRI at 7T. Auditory pathway and various components were revealed by BOLD responses in agreement with the known auditory neuroanatomy by other methods. Tonotopic mapping in inferior colliculus was also demonstrated for the first time by fMRI. Such non-invasive study of functional hemodynamic responses in auditory system will provide a valuable tool in hearing research of normal and diseased models. This was by far the first BOLD fMRI study of rodent auditory system.
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