Abstract #3710

Imaging of Inflammation in the Peripheral Nervous System by 19F MRI

Thomas Christian Basse-Luesebrink¹, Gesa Weise², Carsten Wessig², Peter Michael Jakob¹, Guido Stoll²

¹Experimental Physics 5, University of Wuerzburg, Wuerzburg, Bavaria, Germany; ²Neurology, University of Wuerzburg, Wuerzburg, Bavaria, Germany

Inflammatory cells play an important role in the pathophysiology disorders of the nervous system. Iron oxide-based contrast agents are commonly used to visualize neuroinflammation by magnetic resonance imaging (MRI). Unfortunately, local hemorrhages, blood pool effects and passive diffusion of iron oxide particles through a defective blood-nerve barrier can hamper the information gained.