Axel Joachim Krafft1, Florian Maier1,
Jaane Rauschenberg1, Joshua P. Yung2, Jrgen Walter
Jenne3,4, Wolfhard Semmler1, Michael Bock1
1Medical Physics in
Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany; 2Imaging
Physics, University of Texas M.D. Anderson Cancer Center, Houston, TX, United
States; 3Mediri GmbH, Heidelberg, Germany; 4Clinical
Clinical Cooperation Unit Radiation Oncology, German Cancer Research Center
(DKFZ), Heidelberg, Germany
MR temperature mapping is an indispensable tool for thermal therapies. The most widely used thermometry technique employs temperature induced shifts of the proton resonance frequency (PRF). Spoiled gradient echo (GRE) techniques in combination with long echo times are commonly used to detect the small PRF shifts by the subtraction of phase images. In this work, we present a novel imaging strategy for PRF-based thermometry employing a 90-magnetization preparation to convert temperature related phase changes into a modulation of the longitudinal magnetization. The obtained signal modulation can be detected with fast GRE sequence, and thus, a short TA can be achieved.
Keywords