Alkathafi ALI Alhamud1, Aaron Hess1, Matthew Dylan Tisdall2, Ernesta M. Meintjes1, Andre J. van Der Kouwe2
1University of Cape Town, Cape Town, South Africa; 2Department of Radiology, Harvard Medical School, MA, United States
This paper presents a novel technique to correct, in real time, spatial misalignment of diffusion volumes. A 3D low resolution navigator based on T1 weighted imaging is inserted between the diffusion volumes to compensate for rotation and translation in all 6 degrees of freedom using PACE. The DTI sequence was modified and ran three (Moco, NoMoco and Baseline) on a subject. The results show a substantial improvement in the diffusion tensor parameters with Moco, also the FA histogram shows a shift and a broadening in the FA distribution with NoMoco data, while a significant recovering with Moco was noted.