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Abstract #3962

Clinically Feasible Crossing Fiber Tractography Based on Additional Local HARDI

Kenji Ito1, Yoshitaka Masutani1,2, Yuichi Suzuki2, Shigeki Aoki3, Osamu Abe4, Akira Kunimatsu1,2, Kuni Ohtomo1,2

1Graduate School of Medicine Univ. of Tokyo, Bunkyo-ku, Tokyo, Japan; 2Univ. of Tokyo Hospital, Bunkyo-ku, Tokyo, Japan; 3Radiology, Juntendo Hospital, Bunkyo-ku, Tokyo, Japan; 4Radiology, Nihon University Itabashi Hospital, Itabashi-ku, Tokyo, Japan

Although HARDI (High Angular Resolution Diffusion Imaging) acquisition techinique is essential for crossing fibers analysis, its limitation for clinical situation is the long scan time. We propose a clinically feasible scheme; local-HYDI (Hybrid Diffusion Imaing), which combines whole brain imaging using LARDI (Low Angular Resolution Diffusion Imaging) and local brain imaging with HARDI for crossing fibers volume. Using the local-HYDI data, we also present a Hybrid Tractography (HT) technique based on local switching of deterministic and probabilistic techniques according to data type (LARDI or HARDI) of the location. In this abstract, we evaluated the feasibility of our local-HYDI and HT.