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Abstract #4004

Temporal & Extra-Temporal Perfusion Abnormality in Mesial Temporal Lobe Epilepsy Revealed by Arterial Spin Labeling(ASL)-Based MRI

Guangming Lu1, Zhiqiang Zhang1, Cuiping Yuan1, Lianfang Shen1

1Department of Radiology, Jinling hospital, Nanjing University School of Medicine, Nanjing, Jiangsu, China, People's Republic of

Interictal single-photon emission computed tomography (SPECT) studies have demonstrated that there is hypoperfusion within the extra-temporal structures besides to the temporal lobe in mesial temporal lobe epilepsy (mTLE), which contributes to the proposal of concept of the mesial temporal lobe epilepsy network [1]. The purpose of this study was to determine the feasibility of detecting perfusion abnormalities in mTLE using arterial spin labeling (ASL)-based MRI, which is a noninvasive method for calculating regional cerebral blood flow (rCBF).