Brian A. Taylor1, Adam Winchell1,2, Jan Sedlacik1, Alberto Broniscer3, Ruitian Song1, Ralf B. Loeffler1, Claudia M. Hillenbrand1
1Radiological Sciences, St. Jude Children's Research Hospital, Memphis, TN, United States; 2Biomedical Engineering, University of Memphis, Memphis, TN, United States; 3Oncology, St. Jude Children's Research Hospital, Memphis, TN, United States
An algorithm that combines dynamic susceptibility contrast (DSC) and arterial spin labeling (ASL) imaging for quantitative perfusion measurements was evaluated in a large clinical study in children with diffuse pontine glioma. DSC measurements were calibrated to ASL measurement in voxels with low transit times. An alternative method was evaluated which calibrated DSC to ASL in the gray matter.