Abstract #4153

Morphometric & Functional Connectivity Correlates of Hippocampal Changes in Migraine Frequency

Nasim Maleki¹, Gautam Pendse¹, Lauren Nutile², Rami Burstein³, Lino Becerra^1,4, David Borsook¹

¹P.A.I.N. Group, Brain Imaging Center, McLean Hospital, Department of Psychiatry, Harvard Medical School, Belmont, MA, United States; ²Department of Psychology, Villanova University, Villanova, PA, United States; ³Department of Anesthesia & Critical Care, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA; ⁴Department of Radiology, Massachusetts General Hospital, Charlestown, MA

The role of the hippocampus in migraine has not been well characterized. In this study we assessed whether there are any anatomical changes in the hippocampus in migraine patients based on the frequency of their migraine attacks and what the corresponding functional connectivity correlates are.