Abstract #4229

Brain Function Mapping of Pre-Mild Cognitive Impairment

Amir M. Abduljalil¹, Doug Scharre², Nicoleta Stoicea², Ananth Narayanan³, Michael Knopp¹, Petra Schmalbrock¹

¹Wright Center of Innovation, Radiology Department, the Ohio State University, Columbus, OH, United States; ²Neurology Department; ³Interdisciplinary Graduate Studies Program

Preliminary results were presented from an ongoing functional study of pre-Mild Cognitive Impairment (pre-MCI) patients. Published studies indicate that fMRI can be effective to study MCI patients. This objective of this study is to identify tasks and functional areas of the brain associate with pre-MCI. The tasks studied included attention, verbal fluency, visuospatial problem solving, and memory. Significant brain activations were found as a result of the attention, verbal fluency, Visuospatial problem solving task. The memory paradigm used did not show significant activation compared to the normal group which may be due to the mild state of the disease.