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Abstract #4229

Brain Function Mapping of Pre-Mild Cognitive Impairment

Amir M. Abduljalil1, Doug Scharre2, Nicoleta Stoicea2, Ananth Narayanan3, Michael Knopp1, Petra Schmalbrock1

1Wright Center of Innovation, Radiology Department, the Ohio State University, Columbus, OH, United States; 2Neurology Department; 3Interdisciplinary Graduate Studies Program

Preliminary results were presented from an ongoing functional study of pre-Mild Cognitive Impairment (pre-MCI) patients. Published studies indicate that fMRI can be effective to study MCI patients. This objective of this study is to identify tasks and functional areas of the brain associate with pre-MCI. The tasks studied included attention, verbal fluency, visuospatial problem solving, and memory. Significant brain activations were found as a result of the attention, verbal fluency, Visuospatial problem solving task. The memory paradigm used did not show significant activation compared to the normal group which may be due to the mild state of the disease.