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Abstract #4241

Isotropic Multispectral QMRI with the Mixed-TSE Pulse Sequence & SENSE: Implications for Synthetic-MRI

Stephan William Anderson1, Osamu Sakai1, Memi Watanabe1, Jorge A. Soto1, Hernan Jara1

1Radiology, Boston University Medical Center, Boston, MA, United States

Purpose: To develop a pulse sequence for isotropic multispectral (PD, T1, T2) qMRI with clinically compatible scan times. Methods: A variant of the mixed turbo spin echo pulse sequence with parallel imaging (SENSE) and with true isotropic spatial resolution (voxel=1.25mm3) was implemented at 3T. Results: Isotropic volumetric PD, T1, and T2 maps were generated and used for synthetic MRI. Conclusion: Isotropic multispectral qMRI is feasible in clinically compatible times allowing for accurate multiplanar qMRI and synthetic MRI.