T2* Myelin Water Imaging with BmGESEPI for Macroscopic Field Inhomogeneity Compensation

Yoonho Nam¹, Eung-Yeop Kim², Dosik Hwang¹, Dong-Hyun Kim¹

Myelin water imaging is a useful tool for studying white matter diseases. So far, a multi-exponential T2 analysis using multi-echo spin echo sequence has been mostly used for myelin water imaging. But, using a multi-echo spin echo sequence has some limitations such as high SAR, small coverages. Therefore, several studies have been conducted using multi-echo gradient echo sequences recently. However, T2* decay curve measured by gradient echo sequence can be easily distorted by macroscopic field inhomogeneity. In this study, the bmGESEPI method was applied for myelin water imaging to remove the effects of macroscopic field inhomogeneity.