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Abstract #4558

Accurate T2 Mapping with Dual Echo-FSE: Effect of Phase Encoding Profile Orders

Stephan William Anderson1, Osamu Sakai1, Jorge A. Soto1, Hernan Jara1

1Radiology, Boston University Medical Center, Boston, MA, United States

Purpose: To develop a method for correcting phase encoding profile order effects that can increase the accuracy of T2 qMRI with DE-FSE sequences. Methods: Algorithm incorporating such effects is developed and tested with data of the ACR MRI accreditation phantom and of the brain of a research subject. Results: The correction method leads to T2 values in excellent agreement to those reported with CPMG-32 echoes. Conclusion: Accuracy of T2 qMRI with the DE-FSE pulse sequence can be improved by correcting for profile order effects. This work could have implications for large scale studies using DE-FSE pulse sequences.