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Abstract #4559

Elimination of Susceptibility-Induced Distortion in the T2*-Decay Curve with an Improved Fitting Procedure

Pei-Hsin Wu1, Nan-Kuei Chen2, Hsiao-Wen Chung1

1Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan, Taiwan; 2Brain Imaging & Analysis Center, Duke University Medical Center, Durham, NC, United States

The accuracy of T2* quantification plays an important role in many researches and applications. However, when there exists background susceptibility field gradients, T2* values may be distorted due to TE-shifting effect and echo-shifting effect. In this study, we proposed an improved fitting procedure to quantify the GTE and Gky for correcting TE-shifting effect and avoiding signal-loss artifact from echo-shifting effect. Experimental results in the phantom and human brain suggest that