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Abstract #4623

Post Processing Correction of Ghosting Artefacts in Arterial Input Function Determination for Fast Dynamic Contrast Enhanced MRI

Hendrik Laue1, Dennis Doelschel2, Felix Gremse2, Matthias Gnther1, Fabian Kiessling2, Heinz-Otto Peitgen1

1Fraunhofer MEVIS, Bremen, Germany; 2Experimental Molecular Imaging, RWTH (University of Aachen), Aachen, Germany

Quantitative DCE-MRI requires fast sampling of the AIF. Fast aquisitions are prone to artifacts such as ghosting. We compared two methods correcting AIF measurements and compared the results on 10 Datasets. The first method removes affected timepoints by identifying increased signal outside the body. The second method splits the images and rejoins it so that the signal lost by the ghosting is recollected. Both methods yield an improvement. The first shows a strong improvement performs better but at the cost of about half of the time-points. The second is not as strong but conserves all time-points.