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Abstract #4662

Understanding the Principles & the Challenges of Intravoxel Voxel Incoherent Motion MRI

Christian Federau1, Reto Meuli1, Philippe Maeder1, Patric Hagmann1

1Department of Radiology, University Hospital Center & University of Lausanne, Switzerland, Lausanne, Switzerland

Separation of diffusion and perfusion signal is a possible application of the intravoxel incoherent motion MR imaging method. While the measurement of diffusion showed a wide variety of clinical applications in the past 20 years, the measurement of perfusion using the IVIM method remained confined to a few sporadic publications, due to low signal-to-noise ratio, but showed nevertheless promising results. In the context of impressive improvements in the last few years in terms of both the hardware and software technology, the IVIM method for measuring perfusion is back in focus.