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Abstract #4683

Biophysical Principles & Models of SSFP Functional MRI Contrast Mechanisms in the Brain at High & Ultra-High Magnetic Fields

Irtiza Ali Gilani1, Raimo Sepponen2

1Advanced Magnetic Resonance Imaging Centre, Low Temperature Laboratory, Aalto University, Espoo, Uusima, Finland; 2Department of Electronics, Aalto University, Espoo, Uusima, Finland

Intrinsic short repetition times and short data acquisition periods of the balanced steady-state free precession (bSSFP) fMRI scheme allows 3D, distortion-free, isotropic and high-resolution MR imaging. In this work, the principles of classification of the bSSFP fMRI methods for the brain are reviewed. Different modeling methodologies for bSSFP functional contrast are described. Furthermore, a nonbalanced SSFP fMRI is also reviewed. Feasibility analysis of balanced and non-balanced techniques at the high and ultra-high magnetic fields is presented. Additionally, new models for SSFP fMRI contrast in the brain are suggested.