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Abstract #4684

T1 Mapping: Methods & Challenges

Nikola Stikov1, Christine L. Tardif1, Joelle K. Barral2, Ives Levesque2, G. Bruce Pike1

1Montreal Neurological Institute, McGill University, Montreal, QC, Canada; 2Electrical Engineering, Stanford University, Stanford, CA, United States

In this educational abstract, we provide an overview of the main T1 mapping methods and we outline the challenges in performing quantitative T1 measurement. We describe the gold standard (Inversion Recovery), as well as two widely used alternative methods (Look-Locker and Variable Flip Angle) that speed up the scanning and fitting procedures at the expense of accuracy and precision. The e-poster will include sample T1 maps of phantoms and in-vivo human brains acquired with each of the above methods, and it will provide a list of useful T1 mapping references.