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Abstract #0089

An Integrated Pencil-Beam Probe for Assessing the Arterial Input Function in Quantitative 3D Myocardial Perfusion Imaging

Lukas Wissmann1, Johannes F.M. Schmidt1, Robert Manka1, 2, Sebastian Kozerke1

1Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland; 2Department of Cardiology, University Hospital Zurich, Zurich, Switzerland

The tracer dose in dynamic contrast-enhanced magnetic resonance imaging is crucial for myocardial perfusion quantification. Higher dose is beneficial for myocardial signal-to-noise ratio, but increases the risk of left-ventricular signal saturation in the image due to shorter T1. This study introduces a new acquisition method for the arterial input function using a pencil-beam probe. It is demonstrated that signal saturation in the probe can be avoided by reducing the delay after the saturation pulse. Perfusion quantification from 3D perfusion imaging with the pencil beam probe versus image based assessment of the arterial input function at half and full dose is shown.