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Abstract #0099

Resting State CBF with PASL in Developing Brains

Feng Liu1, 2, Yunsuo Duan1, 2, Bradley S. Peterson1, 2, Alayar Kangarlu1, 2

1Columbia University, New York, NY, United States; 2New York State Psychiatric Institute, New York, NY, United States

Studying the characteristics of cerebral blood flow (CBF) during resting state can help us understand the functional connectivity of the developing brain. We have collected pulsed ASL data for 28 healthy subjects from young children to adolescence (aged from 6 to 20 years old). We studied the static CBF maps during resting state and also used ROI seed-based analysis on the CBF time series to analyze brain connectivity. By showing the changing characteristics of CBF in differing age groups, we are able to better understand the development of brain connectivity.