Abstract #0333

Simultaneous Small Animal PET/MR in Activated and Resting State Reveals Multiple Brain Networks

Hans F. Wehrl¹, Konrad Lankes¹,², Mosaddek Hossain¹, Ilja Bezrukov¹,³, Chih-Chieh Liu¹, Petros Martirosian⁴, Gerald Reischl¹, Fritz Schick⁴, Bernd J. Pichler¹

¹Department for Preclinical Imaging and Radiopharmacy, University of Tuebingen, Tuebingen, Germany; ²Bruker BioSpin MRI, Ettlingen, Germany; ³Max Planck Institute for Intelligent Systems, Tuebingen, Germany; ⁴Section on Experimental Radiology, University of Tuebingen, Tuebingen, Germany

Simultaneous small animal PET/MR allows the study of functional processes on multiple levels. Here we present a comparison between simultaneous activation as well as resting state fMRI and PET in rats. Additional activated components of brain networks are found in PET, not present in fMRI. The data show complementarities of both techniques in respect to activation as well as default mode network imaging in the brain.