Meeting Banner
Abstract #0333

Simultaneous Small Animal PET/MR in Activated and Resting State Reveals Multiple Brain Networks

MAGNA25Hans F. Wehrl1, Konrad Lankes1, 2, Mosaddek Hossain1, Ilja Bezrukov1, 3, Chih-Chieh Liu1, Petros Martirosian4, Gerald Reischl1, Fritz Schick4, Bernd J. Pichler1

1Department for Preclinical Imaging and Radiopharmacy, University of Tuebingen, Tuebingen, Germany; 2Bruker BioSpin MRI, Ettlingen, Germany; 3Max Planck Institute for Intelligent Systems, Tuebingen, Germany; 4Section on Experimental Radiology, University of Tuebingen, Tuebingen, Germany

Simultaneous small animal PET/MR allows the study of functional processes on multiple levels. Here we present a comparison between simultaneous activation as well as resting state fMRI and PET in rats. Additional activated components of brain networks are found in PET, not present in fMRI. The data show complementarities of both techniques in respect to activation as well as default mode network imaging in the brain.