DTI Using Modulated Gradients at Short Effective Diffusion Times

Henrik Lundell¹, Casper Kaae Snderby¹, Lise Vejby Sgaard¹, Tim Bjrn Dyrby¹

Assessment of short term self diffusion processes using oscillating gradient techniques is a topic of recent interest with promising applications in microstructure imaging. In this study we implement a trapezoidal modulated gradient sequence for diffusion tensor imaging and apply it on a perfusion fixed monkey brain sample. We find increased diffusivities in white matter at short effective diffusion times, but overall maintained anisotropy. However, new features emerge at short diffusion times that could be related to microstructures not visible with conventional techniques.