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Abstract #0355

DTI Using Modulated Gradients at Short Effective Diffusion Times

Henrik Lundell1, Casper Kaae Snderby1, Lise Vejby Sgaard1, Tim Bjrn Dyrby1

1Copenhagen University Hospital Hvidovre, Danish Research Centre for Magnetic Resonance, Hvidovre, Copenhagen, Denmark


Assessment of short term self diffusion processes using oscillating gradient techniques is a topic of recent interest with promising applications in microstructure imaging. In this study we implement a trapezoidal modulated gradient sequence for diffusion tensor imaging and apply it on a perfusion fixed monkey brain sample. We find increased diffusivities in white matter at short effective diffusion times, but overall maintained anisotropy. However, new features emerge at short diffusion times that could be related to microstructures not visible with conventional techniques.