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Abstract #0649

GRAPPA-Accelerated Dual-Echo Diffusion-Weighted EPI with Intensity Correction

Samantha J. Holdsworth1, Stefan Skare2, Matus Straka1, 3, Manabu Inoue3, Roland Bammer1

1Department of Radiology, Stanford University, Palo Alto, CA, United States; 2Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden; 3Stanford Stroke Center, Stanford University Medical Center, Stanford University, Palo Alto, CA, United States

Geometric distortion in single-shot (ss)-EPI used for diffusion-weighted imaging (DWI) can be reduced through the use of parallel imaging, however the shorter TE results in images which can have lower lesion sensitivity. Thus, to benefit from both increased image quality through the use of parallel imaging as well as the increased sensitivity of lesions through higher echo times, here we implement a GRAPPA-accelerated dual-echo EPI DWI sequence on stroke patients and present our preliminary data. We also demonstrate how one can utilize the two echoes to remove the coil sensitivity which removes the need for an additional calibration scan.