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Abstract #0801

Investigation of T2* Mapping on Combat-Related TBI Patient

Binquan Wang1, 2, Ping-Hong Yeh1, 2, Wei Liu1, 2, John Graner3, 4, Haiying Tang, 25, Hai Pan1, 2, Dominic E. Nathan1, 2, Rachel Wolfowitz4, Jamie Harper4, John Ollinger4, Terrence R. Oakes, 24, Gerard Riedy4, 5

1Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, United States; 2Center for Neuroregenerative Medicine, Bethesda, MD, United States; 3National Capital Neuroimaging Consortium, Bethesda, MD, United States; 4National Intrepid Center of Excellence (NICOE), Bethesda, MD, United States; 5Uniformed Services University of The Health Sciences of The Health, Bethesda, MD, United States

T2* mapping of combat-related TBI patients were investigated. The T2* mapping demonstrates the advantage to detect the brain lesions as previous studies. And both of voxel wise and ROI analysis shows TBI patients had significantly longer T2* relaxation time than healthy controls. And the positive relationship was illustrated by the regression between T2* and neurobehavioral symptoms. Our findings may be used to predict the clinical symptoms of military-related TBI patients.