Ji-Young Kim1, Jeehye Seo2, Hui-jin Song2, Seong-Uk Jin2, Jang Woo Park2, Moon Han2, Jong Su Baeck2, Hee-Kyung Kim3, Yongmin Chang4
1School of Medicine, Kyungpook National University, Daegu, Jung-gu, Korea, Republic of; 2Medical & Biological Engineering, Kyungpook National University, Korea, Republic of; 3Applied Chemistry, Kyungpook National University, Korea, Republic of; 4Molecular Medicine, Kyungpook National University, Korea, Republic of
Stroke patients with hand function in severe hemiplegic are known to be determined their prognosis at acute period of stroke. Brunnstrum motor recovery stage (BMS) and motor evoked potential (MEP) have been used to predict prognosis in stroke patients well. Using the BMS and MEP, stroke patients who have no MEP of affected hand or no hand movement with BMS 1 in 4 weeks from onset of stroke were usually regarded as that with poor prognosis. Nevertheless, most patients regarded as poor prognosis could recover their hand function. Recent researchers revealed functional connectivity of homologous primary motor cortex as a prognostic factor in stroke patients. The aim of this study is to (1) compare inter-hemispheric functional connectivity scores with in homologous M1 among stroke patients groups which showed different recovery patterns by means of resting state fMRI and (2) find good prognostic phenomeni to severe hemiplegic stroke patients who had no hand movement with BMS 1 and MEP response by means of fMRI with passive movement.