Abstract #0835

Detection of Radiation Therapy Induced Cerebral Microbleeds in Gliomas: Does High Field Mean High Yield?

Wei Bian¹,², Christopher Hess¹, Susan Chang³, Sarah Nelson¹,², Janine Lupo¹

¹Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, United States; ²Joint Graduate Program in Bioengineering, University of California San Francisco & Berkeley, San Francisco, CA, United States; ³Neurological Surgery, University of California San Francisco

The goal of this study was to compare the detection of radiation-induced cerebral microbleeds (CMBs) in glioma patients between 3T and 7T and magnitude and SWI reconstructions. Ten patients who received prior radiation therapy were scanned using T2*-weighted gradient-echo imaging at both 3T and 7T. Our results showed that although the sensitivity of CMB identification increases with field strength, the heighted susceptibility artifacts present at 7T often limited their detection. To achieve the highest detection rate of CMBs for these patients, SWI should be utilized even at 7T, and tumor location should be considered when deciding field strength.