Abstract #1016

Evaluation of USPIO Uptake to Assess the Risk of Future Cerebrovascular & Cardiovascular Events: Long-Term Follow-Up of the ATHEROMA Trial

Andrew J. Patterson¹, Andrew J. Degnan¹, Martin J. Graves¹, Tjun Y. Tang², Jonathan H. Gillard¹

¹Department of Radiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, England, United Kingdom; ²Department of Vascular Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, England, United Kingdom

A long-term follow-up study assess if USPIO intra-plaque uptake is predictive of subsequent cerebrovascular and cardiovascular events. Sixty-two patients were followed for a median of 4 years in which 17 patients had subsequent events. Survival regression models are applied to assess if signal intensity change following USPIO is predictive of events.