Matthew P. Quinn1, L. Martyn Klassen2, Joseph S. Gati2, Ravi S. Menon, 12
1Medical Biophysics, The University of Western Ontario, London, Ontario, Canada; 2Robarts Research Institute, London, Ontario, Canada
A novel post-processing scheme is presented for multi-echo susceptibility weighted imaging (SWI) that uses a mask derived from a frequency image. The performance of this frequency-based SWI is compared with two other previously reported multi-echo SWI schemes and single-echo SWI in healthy volunteers at 3 T. Frequency-based SWI shows significantly larger increases relative to single-echo SWI in signal to noise measured in frontal white matter, as well as in contrast to noise of periventricular veins, optic radiations, and globus pallidus, compared to previously described multi-echo SWI. In conclusion, frequency-based SWI shows improvements in visibility of a variety of field perturbers.