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Abstract #1116

Two Lipid Pools Detected in the Myocardium of Rats Fed a High Fat Diet

Vijayasarathi Nagarajan1, Philip William Kuchel1, S. Sendhil Velan1

1Laboratory of Molecular Imaging, Singapore Bioimaging Consortium, Singapore, Singapore


We evaluated the myocardial fat content in rats fed with a placebo and a high fat diet. We demonstrated the presence of two lipid pools in the myocardium of the rats with obesity induced by high fat diet. The left ventricular function was significantly reduced in rats fed with high fat diet. The concentration of IMCL in myocardium may be a potential marker for early stages of diabetes.

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