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Abstract #1287

Fast T1 Mapping for Liver Function Estimation Using Gd-EOB-DTPA

Tetsuya Wakayama1, Keizo Miyakoshi2, Daisuke Nishiyama2, Masahiro Okada3, Hiroyuki Kabasawa1, Tatsuro Uto2, Takamichi Murakami3

1Global Applied Science Laboratory, GE Healthcare, Hino, Tokyo, Japan; 2Department of Radiological Technology, Kinki University Hospital, Japan; 3Department of Radiology, Kinki University Faculty of Medicine, Japan

A novel approach to three dimensionally measure T1 value of liver with IR-based multiple breath-holding acquisitions was developed and demonstrated in this study. The phantom validation revealed that 3D T1map developed here could provide acceptable accuracy of T1 with larger volume coverage and less scan time, compared with 2D T1map acquired by conventional 2D IR-FSE. In volunteer examination, 3D T1map was successfully obtained from liver. This approach can be expected to three dimensionally evaluate T1 of the liver with clinically acceptable scan time.