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Abstract #1446

Investigation of Human Quadriceps Variation on Resting Muscle Stiffness and Brain Activation During Contraction

Paul Kennedy1, Scott Semple1, Calum Gray1, Annette Cooper1, Eric Barnhill1, Colin Brown2, David Donaldson3, Edwin van Beek1, Pete Hoskins, Dieter Klatt4, Ingolf Sack4, Jrgen Braun4, Carolyn Greig, Angus Hunter5, Neil Roberts1

1Clinical Research Imaging Centre, University of Edinburgh, Edinburgh, United Kingdom; 2The Mentholatum Company, East Kilbride, Glasgow, United Kingdom; 3Department of Psychology, University of Stirling, Stirling, United Kingdom; 4Charit University, Berlin, Germany; 5Health and Exercise Sciences Research Group, University of Stirling, Stirling, United Kingdom

We present our ongoing work on the investigation of human skeletal muscle using MRI. We outline the variations in muscle morphology seen and how they correlate with stiffness measurements obtained by magnetic resonance elastography.