Abstract #1446

Investigation of Human Quadriceps Variation on Resting Muscle Stiffness and Brain Activation During Contraction

Paul Kennedy¹, Scott Semple¹, Calum Gray¹, Annette Cooper¹, Eric Barnhill¹, Colin Brown², David Donaldson³, Edwin van Beek¹, Pete Hoskins, Dieter Klatt⁴, Ingolf Sack⁴, Jrgen Braun⁴, Carolyn Greig, Angus Hunter⁵, Neil Roberts¹

¹Clinical Research Imaging Centre, University of Edinburgh, Edinburgh, United Kingdom; ²The Mentholatum Company, East Kilbride, Glasgow, United Kingdom; ³Department of Psychology, University of Stirling, Stirling, United Kingdom; ⁴Charit University, Berlin, Germany; ⁵Health and Exercise Sciences Research Group, University of Stirling, Stirling, United Kingdom

We present our ongoing work on the investigation of human skeletal muscle using MRI. We outline the variations in muscle morphology seen and how they correlate with stiffness measurements obtained by magnetic resonance elastography.