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Abstract #1447

Pitfalls in Cuff-Induced Ischemia Studies Using BOLD MRI

David K.W. Yeung1, James F. Griffith2, Heather T. Ma2, 3, Alvin F.W. Li

1Imaging and Interventional Radiology, Prince of Wales Hospital, Shatin, HKSAR, Hong Kong; 2Imaging and Interventional Radiology, The Chinese University of Hong Kong, Shatin, Hong Kong; 3Department of Electronic and Information Engineering, Harbin Institute of Technology, China


Muscle perfusion may be studied using the BOLD technique. This method relies on an air-cuff to induce reactive hyperemia. However, oxygen in air is a paramagnetic molecule and whether an inflated air-cuff has an effect on T2* signal measurement is not known. This study attempts to answer this question and offers solutions to correct for aberrant T2* signal changes.

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