Abstract #1476

Dynamic Analysis of Breast Lesions: Can We Use the Wash-In Phase Instead of the Wash-Out Phase?

Ritse M. Mann¹, Roel DM Mus¹, Christian Geppert², Cindy PM Frentz¹, Nico Karssemeijer¹, Henkjan Huisman¹, Bram Platel¹,³

¹Radiology, Radboud University Nijmegen Medical Centre, Nijmegen, Gld, Netherlands; ²Oncology, Siemens Healthcare, Erlangen, Germany; ³Fraunhofer MEVIS, Bremen, Germany

Initial maximum slope of enhancement as derived from ultrafast TWIST images acquired during contrast inflow provides a strong discriminator between benign and malignant disease that outperforms classic 3-timepoint analysis. By using a fixed grid of relative enhancement versus time curve types can be defined that can be easily implemented in current radiological practice.