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Abstract #1501

Quantification of Prostate Metabolites at 3 T Using Water as the Internal Reference

Jan Weis1, Francisco Ortiz-Nieto1, Hkan Ahlstrm1

1Department of Radiology, Uppsala University Hospital, Uppsala, Sweden

Metabolite concentrations may be helpful in monitoring treatment efficacy, and relapse probability associated with prostate cancer. Single-voxel spectroscopy of the prostate at 3 T with surface coil was performed. Metabolite-to-unsuppressed water spectral intensity ratios of healthy volunteers and patients with biopsy-proven prostate cancer were determined with an LCModel. Mean normalized spectra, LCModel fits, and absolute concentrations of Cho, Cr, and Cit were computed for normal volunteers and cancer patients.