Abstract #1502

Contrast Agent-Free High Resolution MRI for Prostate Cancer Detection Using a Two Compartment Inversion Recovery (TCIR) Technique.

Patrik Zamecnik¹, Grzegorz Bauman², Julien Dinkel¹,³, Heinz-Peter Schlemmer¹, Thomas Gaass⁴

¹Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany; ²Department of Medical Physics, German Cancer Research Center (DKFZ), Heidelberg, Germany; ³Department of Radiology, Massachusetts General Hospital, Boston, Germany; ⁴Zentralinstitut fr Medizintechnik, Technische Universitt Mnchen, Garching, Germany

Validation of the feasibility of TCIR (two compartment inversion recovery) contrast agent-free approach for prostate cancer detection by comparison with the standard T2w, DCE- and DWI-sequences. Using the TCIR technique it was possible to generate good quality high-resolution maps of the fractional blood volume in the prostate without using a contrast agent. TCIR has a high potential for prostate cancer detection because of its high spatial resolution and sensitivity, first of all in patients, which cannot be examined using contrast media.