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Abstract #1569

Different Indication of FLAIR, Contrast-Enhanced, and MTR Images on Tissues Ablated by High-Intensity Focused Ultrasound

Shih-Chieh Lin1, Teng-Yi Huang2, Wen-Shiang Chen3, Jyun-Ming Tsai2, Meng-Ju Wang3, Wen-Yih Isaac Tseng4, Hsu-Hsia Peng1

1Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua Univisity, Hsinchu, Taiwan; 2Department of Electrical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan; 3Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Taipei, Taiwan; 4Center for Optoelectronic Biomedicine, Medical College of National Taiwan University, Taipei, Taiwan

Evaluation of longitudinal tissue property alterations following HIFU ablation is important in the monitoring of therapeutic effects. Our previous studies, presented a designed pulse sequence which can evaluate temperature and MT effect simultaneously during HIFU transmission, have been performed on ex-vivo porcine muscle studies and in-vivo rabbit thigh muscle studies. In this study, we aim to compare the complimentary information of ablated regions provided by MT effect and routine images. The FLAIR images, T1-weighted contrast-enhanced images, and MT-weighted images are acquired in long-term follow-up experimental design. Different indication of above three kinds of image contrast is demonstrated in this study.