Abstract #1570

Evaluation of PRFS MR Thermometry in the Human Prostate Gland at 3.0T for Transurethral Ultrasound Therapy

Elizabeth Ramsay¹, Charles Mougenot², Max Kohler², Michael Bronskill³, Laurence Klotz⁴, Masoom Haider⁵, Rajiv Chopra¹,³

¹Imaging Research, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; ²Philips Healthcare; ³Department of Medical Biophysics, University of Toronto; ⁴Department of Urology, Sunnybrook Health Sciences Centre; ⁵Medical Imaging, Sunnybrook Health Sciences Centre

A segmented gradient echo EPI sequence as applied to PRF shift thermometry was evaluated in healthy human volunteers at 3T in order to determine its feasibility for MRI-controlled transurethral prostate therapy. TE values of 7-25ms, EPI factors of 5-17 and voxel sizes from 1.14mm to 2.0mm were tested. For all scan parameters and for all volunteers, the temperature standard deviation within the prostate was less than 1^oC, while the spatial distortion was less than 1mm.