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Abstract #1603

Novel MR-Safe Guidewire with Passive Iron-Platinum Alloy Nanoparticles for MR-Guided Interventions

Martin Alexander Rube1, Patricia Seifert2, Bernhard Uihlein2, Dhanapriya Kakchingtabam3, Pascal Andr3, Andreas Melzer1

1Institute for Medical Science and Technology, University of Dundee, Dundee, United Kingdom; 2EPflex Feinwerktechnik GmbH, Dettingen, Germany; 3School of Physics and Astronomy (SUPA), University of St Andrews, St. Andrews, United Kingdom

A safe and reliable method for localising interventional devices is being developed to facilitate MR guided vascular intervention, which has valuable attributes (e.g. reduced radiation dose, functional information, high soft tissue contrast, and generally no need for contrast agents). The proposed device localisation aproach is based on biocompatible iron-platinum alloy (FePt) nanoparticles in a polymeric matrix and has been applied to a novel MR safe guidewire.