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Abstract #1718

Distinguishing GABA from Lysine In Vitro and in vivo by 2D Localized Correlated Spectroscopy

Luke Yuan-Je Wang1, 2, Hui Jun Vicky Liao2, Ana K. Cadena2, Saadallah Ramadan3, Carolyn Mountford2, 3, Alexander P. Lin2

1Department of Anesthesiology, Children's Hospital Boston, Boston, MA, United States; 2Department of Radiology, Brigham and Women's Hospital, Boston, MA, United States; 3Faculty of Health, The University of Newcastle, Newcastle, New South Wales, Australia


: Lysine and lysine-containing macromolecules have been hypothesized to co-resonate near GABA in 2D COSY. In this proof-of-concept study, we were able to separate the relevant cross-peaks at 3T In Vitro and in vivo.