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Abstract #1766

Blood Contamination Affects Lipid Quantification in Cardiac 1H MR Spectroscopy

sa Carlsson1, 2, Maja Sohlin2, Maria Ljungberg1, 2, Eva Forssell-Aronsson1, 2

1Department of Medical physics and Biomedical Engineering, Sahlgrenska University Hospital, Gothenburg, Sweden; 2Department of Radiation Physics, University of Gothenburg, Gothenburg, Sweden

Proton MR-spectroscopy is an increasingly popular tool for studying the heart metabolism. For quantification, the triglyceride signal is often related to an internal reference. However, if the volume of interest (VOI) includes any of the ventricular blood those ratios might be affected. In this work, we investigated how the lipid quantification is affected by blood contamination by comparing spectra from VOIs fitted within the ventricular septum with spectra from VOIs enclosing the septum. It is shown that the lipid, water and creatin signal are differently affected by blood contaminations and hence, blood contamination will affect lipid quantification.