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Abstract #1812

Is metabolic Connectivity Across Spared Non-Primary Motor Areas Altered in Stroke?

Carmen M. Cirstea1, 2, Hung-Wen Yeh1, 3, Anda E. Popescu1, Ali Bani-Ahmed1, 2, In-Young Choi1, 4, Phil Lee1, 5, Sorin Craciunas6, William M. Brooks1, 4

1Hoglund Brain Imaging Center, University of Kansas, Kansas City, KS, United States; 2Departments of Physical Therapy; 3Biostatistics; 4Neurology; 5Molecular & Integrative Physiology, University of Kansas, Kansas City, KS; 6Neurosurgery Unit IV, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania

Although metabolite abnormalities have been documented in survivors of stroke by magnetic resonance spectroscopy, the relationship between metabolites in discrete anatomic areas that form cognitive networks is less well understood. Our goals were to establish evidence of "metabolic connectivity" in normal brain and to determine whether such connectivity was altered in radiologically normal appearing cortex following a sub-cortical stroke.